Why does the new corona virus disease worsen?

 


It has been more than half a year since the outbreak of the new corona pneumonia virus, and the entire planet has been occupied by the virus. The people and economies of all countries are in huge distress, and so far there is no sign of relief. Fortunately, compared with some of the great plagues in history, the new coronavirus, although highly contagious, is not very deadly. However, there are still hundreds of thousands of people who have lost their lives because of the virus. So why do some people get better soon after being infected, while some people have to pay the price of their lives?

A study published in the journal Nature on September 30 showed that something left by another race of Neanderthals in our ancestors' bodies 60,000 years ago may be responsible for this difference. This study comes from Hugo Zeberg and Svante Paabo of the Max Planck Institute for Evolutionary Anthropology in Germany. It tested 3199 hospitalized patients with new coronary pneumonia and a control group. In the study, researchers found that a gene segment on human chromosome 3 that affects the severity of patients with new coronary pneumonia was inherited from Neanderthals 60,000 years ago.

Humans have 23 pairs of 46 chromosomes, and each chromosome has 38 to 250 million, for a total of about 3 billion base pairs. In a large international study this summer, scientists have determined that a gene segment on human chromosome 3, about 49,400 base pairs, is closely related to the severity of new coronary pneumonia infection. These genes affect whether the infected person is will get worse and whether hospitalization is needed.

Zeberg and Pabo’s research found that Neanderthals from southern Europe carried almost the same gene fragments, while Neanderthals and Denisovans from southern Siberia did not. Further research has shown that Neanderthals from southern Europe met with two humans about 60,000 years ago, leaving these gene fragments in some human bodies, making them more at risk of getting sicker after being infected with the new crown pneumonia virus. high. According to Professor Zeberg, people with Neanderthal genetic mutations are three times more likely to require ventilator assistance to breathe after being infected with the new corona pneumonia virus. This is the strongest genetic factor.

So where are these people distributed? Researchers have found that about half of the population in South Asia carry this gene, most of them are Bangladeshis. It is estimated that 63% of people have this gene in their bodies, which makes them twice as likely to die from new coronary pneumonia than ordinary people; One in six people in Europe carry this gene, while East Asians and Africans do not.

Professor Pabo said that it is shocking that the genetic heritage of Neanderthals had such tragic consequences during the current pandemic. Scientists are still studying why these gene fragments will increase the condition of coronary pneumonia. It seems that human beings are really good at dumping the pot. They have already dumped Neanderthals on humans suffering from heart disease, high blood pressure, mental illness, nicotine addiction and other diseases. The Det people are on their heads, why did the human ancestors be so unscrupulous in the first place to have such an endless troublesome relationship with the Neanderthals?

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